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Unusual Presentation of Multiple Myeloma

Unusual Presentation of Multiple Myeloma

A case of multiple myeloma presenting with isolated cranial nerve palsy, without the bone pain or renal impairment that usually brings these patients to attention.

Case Presentation

A 62-year-old man presented with six weeks of double vision. Examination showed an isolated sixth nerve palsy. Imaging revealed a clival plasmacytoma; subsequent marrow biopsy confirmed multiple myeloma.

Discussion

Skull-base plasmacytomas are uncommon but worth remembering in any adult with an unexplained cranial neuropathy. Serum free light chains are a cheap and fast first step.

References

  1. Rajkumar SV. Am J Hematol. 2022.

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